Project #1
Ball and Stick
Modelling of a Protein Domain
UPDATE #1: Preliminary Data
Introduction: The
goal of figuring the atomic configurations of molecules has
been difficult to acheive. To know how a protein or other
molecule looks like is very important to understanding its
function and how to enhance or inhibit it. This it turn could
lead to the creation of new drugs and other scientific breakthroughs.
The current methods for determining structure (Nuclear Magnetic
Resonance, X-ray Crystallography, Atomic Force Microscopy,
ect.) all possess advantages and disadvantages that a new
technique may add to the current knowledge base.
Purpose: By creating a protein
out of ball and stick modelling kits it is believed that
several new advantages are possible: The model can be easily
manipulated to observe interactions, large and close-up three
dimensional views may provide new insights, illegitimate
constraints will be easily recognized leading to more accurate
models.
Targets: To be determined.
Protein to be analyzed will either be a full lenght protein
or a protein domain of about 50 amino acids.
Project Cost: $500 - Critical
to the success of this project is a source of model kits
from the same manufacturer so as to maintain correct atomic
distances between atoms. A quick estimate is a model kit
will provide enough componants to construct 4 amino acids,
as 50 are needed, we estimate 13 kits are needed at ~30.00
a piece, plus other needed items.
If you wish to donate to the project, CLICK
HERE